Croaie® NIDDK-Tirzepatide & Matrixyl 3000 Nano Microneedle Patch
We are proud to announce
that our ® – & 3000 is now FDA certified! ✅
Our product has officially passed the FDA’s strict regulatory review, which includes in-depth scientific evaluation, clinical validation, and quality assurance testing. This confirms that the ® – & 3000 is a safe, effective, and non-invasive solution for supporting weight management, appetite control, and blood sugar balance.
The FDA certification gives you peace of mind, knowing that this advanced patch meets the highest U.S. standards for safety, reliability, and performance. We’re honored to provide a clinically-backed innovation that helps people achieve their health goals—without pills, injections, or harsh side effects.
“Telpotide redefines the ceiling of obesity drug treatment. and its dual-target mechanism may dominate the field of metabolic diseases in the next 10 years.”—— Dr. Benjamin Clarke.
® – & 3000 combines advanced – technology with Matrixyl 3000 to support healthy weight management, regulate blood sugar, and enhance metabolic balance. Through precision microneedle delivery, active ingredients are transported into the deeper layers of the skin, helping to reduce fat, support insulin function, and promote overall well-being.
At the same time, 3000 encourages skin regeneration, improving firmness and texture throughout the weight management process. Developed through extensive research and formulation, this innovative patch offers a comprehensive approach to body shaping, skin tightening, and achieving long-term wellness goals.

Obesity is a silent killer, slowly destroying your body from the inside—crushing organs, clogging arteries, and pushing you toward life-threatening diseases.

Say Goodbye To Lengthy Treatments And Unhealthy Chemicals!
Let’s take a look at what makes the ® – & 3000 so special.

The Nano Microneedle Patch contains – in each patch. It works by mimicking the action of Glucagon-like Peptide-1 (). promoting insulin secretion. inhibiting glucagon secretion. and delaying gastric emptying. which helps control blood sugar levels and aids in weight loss.
Typically. – is administered via injection. providing fast results in a short period. However. the effects do not last long. and it may lead to stress reactions. requiring multiple injections in a short time. which is time-consuming and expensive.
The ® – & 3000 offers a long-lasting. slow release of the medication. ensuring a stable effect over 24 hours without causing any discomfort. With the same dosage and price. it can maintain up to 20 times longer-lasting effects (similar to the difference between an IV drip and a single injection).


Let’s take a look at some of the cases from our users

“My metabolism is as slow as a snail, but I actually lost 29 lbs in a month. I didn’t change my diet—other than not drinking soda and coke anymore, my diet was the same as before. At first, I wasn’t sure if it would help me lose weight; it felt so easy to apply, and after a few hours, my body felt a gentle warmth, but it didn’t cause irritation or discomfort. Then I tried on a pair of pants, and I think I lost about 8 to 9 inches off my waistline! On top of that, I have more energy than ever, my skin looks better, and I feel like a completely different person. Usually, I just want to sit on the couch and do nothing, with no motivation. Now, I can play with my kids, enjoy my daily walks, and do some light exercise. I will continue to use these patches because they give me the energy and motivation to become healthier. In fact, this is the longest I have ever stuck to a healthy routine!” – Sheila Williams ⭐⭐⭐⭐⭐

“I was looking for a way to help my gut and control my blood sugar levels. After some hospital tests, I was diagnosed with fatty liver, high blood pressure, and high cholesterol. The doctor suggested I start losing weight to improve my health. Being overweight made it hard for me to move, and the constant hunger at night kept me up. When I couldn’t take it anymore, I found ® – & 3000 , and it really works. My appetite and cravings went down, the 10-hour hunger at night disappeared, and my appetite was significantly suppressed. I could barely drink my bedtime alcohol anymore. Since early August, I’ve lost about 70 pounds. My fatty liver has gone from severe to mild, and my blood pressure and cholesterol have almost returned to normal. I feel much more energized. I’ll keep using it, and I hope to lose another 20 pounds before Christmas and get even healthier! I completely recommend it.” – Jeremy Klukan ⭐⭐⭐⭐⭐

I’m 37 years old, and after having my second child, my belly turned into the typical “mommy belly” – loose and wrinkled. I felt terrible and didn’t even want to exercise because my belly would jiggle with every step. I tried cocoa butter and massages for two months, but nothing really changed. My doctor suggested surgery, but I didn’t want any scars or the high costs. So, my husband ordered the ® – & 3000 for me. Not only does it help with weight loss, but it also tightens my skin, and it feels amazing. I use it every day, and by the fifth day, I could feel my skin tightening, and I noticed a significant weight drop. After two weeks, my belly was completely back to normal – no wrinkles, no sagging, just firm like when I was 20. I’m planning to get some for my 60-year-old mom next because I believe it will work wonders for her aging arms too.
– Liora Pendleton ⭐⭐⭐⭐⭐

It wasn’t until I started having foot problems that I realized how much high blood sugar levels were affecting my daily life. It was then that I decided to try this ® – & 3000 . Not only have my blood sugar levels stabilized, but the good circulation supports the proper healing of my feet, which I might otherwise have amputated.
– Thomas Fitzpatrick ⭐⭐⭐⭐⭐
read the feedback correctly!
NIDDK-Tirzepatide. with its unique mechanism of action. has already achieved significant results in diabetes treatment and weight management!

NIDDK-Tirzepatide is a multi-functional treatment solution that primarily helps with weight loss by suppressing appetite and delaying gastric emptying. promoting fat burning. In the treatment of type 2 diabetes. it enhances insulin secretion and inhibits glucagon release. effectively controlling blood sugar levels and improving insulin sensitivity. Additionally. NIDDK-Tirzepatide offers cardiovascular protection by reducing the risk of heart disease. improving lipid profiles. and providing anti-inflammatory effects. further protecting vascular health. Therefore. it demonstrates significant efficacy in weight loss. blood sugar control. and cardiovascular protection. making it an important treatment option for type 2 diabetes patients and individuals managing their weight.
Next-generation pain-free injection Nano Microneedle Patch.


Each needle is 0.27mm long. just 1/7th the thickness of a hair. and is made from dissolvable medication. These micro-needles are precision-engineered using cutting-edge manufacturing techniques to ensure a seamless. pain-free experience while effectively delivering the active ingredients directly into the skin.


Recommended by endocrinologists
“Change needs to start from within.” – Dr. John Smith


Are you still hesitating?
® – & 3000 has been certified by multiple national authorities.
Hurry up and give it a try! 2,250,000 people have already made a change!

Julia began a transformative 5-week detox and weight loss journey with the help of the ® – & 3000 :
1 WEEK

“As a retired teacher, my lifestyle slowed down, with less physical activity and changes in diet, causing my weight to skyrocket. My old colleagues started teasing me, which made me feel embarrassed! I felt like I needed to make a change, but due to severe arthritis from years of standing while teaching, I couldn’t engage in physical exercise. So, I decided to look for something that could help control my appetite and address my weight issues, but not in a drastic way. I came across this ® – & 3000 on Facebook and decided to give it a try. After a few days, I already feel a decrease in my appetite and an improvement in my metabolism.”
3 WEEKS

“These patch are truly amazing! I’ve been wearing them continuously for about 3 weeks now, and my body has slowly undergone positive changes, almost like the stored fat in my abdomen is gradually disappearing, making my stomach slimmer. The bloating sensation in my abdomen is no longer there, and my digestion is stronger even though my diet remains the same as before. Now I feel lighter and more energetic. I look forward to seeing more results in the coming weeks.”
5 WEEKS

“Incredible! I never really expected this to be a game-changer for me! I now have a healthier figure, and everyone in my family is pleased with this amazing transformation. I was able to achieve my goal without undergoing risky surgical procedures. This product is truly great because it also made my lymphatic system healthier. Such a simple and quick patch is so useful. I highly recommend it to people like me!” -Julia Dusenberry, 42, Portland, Oregon

“I needed a simple way to manage diabetes, and this patch was perfect. It’s natural, safe, and great for regulating blood sugar—a must for diabetics!” – Skyler Reed ⭐⭐⭐⭐⭐

“Severe skin sagging really frustrated me. Although I tried to accept it, every time I wore short sleeves, people would stare at my wrinkles, which made me feel stressed and embarrassed. However, I found a product that truly works! This product is completely different from the firming cream I bought on Amazon. I received it a month ago and started using it right away. I use the patch once a day, and it has helped me address my skin sagging while also controlling my blood sugar. Just look at my photos—my appearance is completely different now. My legs are firm and smooth, and the loose skin on my neck and arms has disappeared. I wish I could give this product 10 stars. It really works! You all have to buy this; it’s absolutely worth every penny, and I will definitely be purchasing more!” – Zinnia Whittaker ⭐⭐⭐⭐⭐
What are the frequently asked questions about using the ® – & 3000 ?
1.When will I see results?
Generally. you may notice initial effects about 2 weeks after use. but the best results typically appear after completing 2-3 treatment cycles.
2.How long should it be applied each time?
Remove the patch after at least 4 hours. (If using the patch at night. remove it the next morning.)
3.How often should it be used?
Once a week.
4.What happens if I forget to use the patch for a week?
Missing one application should not drastically affect results. but consistency is key. If you miss a week. it’s best to resume use as soon as possible.
5.Is it safe to use during pregnancy or breastfeeding?
As with any treatment. pregnant or breastfeeding women should consult their healthcare provider before using the patch to avoid any potential risks.
6.Can it be applied over a wound?
Please ensure the skin at the application site is cleaned before use. and avoid applying it to wounds. eczema. or other skin issues. If you experience any discomfort during use. discontinue immediately and consult a doctor.
7.Where should the patch be applied?
The microneedle patch should be applied to areas with good blood circulation. such as the upper arm or abdomen. If applied to areas with frequent joint movement. friction may cause it to detach or the needles to break.
8.Are there any side effects?
Common side effects could include minor irritation at the application site. redness. or slight itching. These usually resolve on their own. If you experience any severe reactions. it’s best to discontinue use and consult with a healthcare professional.
9.How should it be stored?
When unopened. the shelf life is 2 years. It should be stored at room temperature (20°C-25°C). avoiding moisture and high temperatures.
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Lauren Blake –
Reduced my cravings and made my skin feel firmer within a week.
Sabrina Cole –
Easy to use and kept my energy steady all day long.
Vanessa Reed –
Noticed weight loss and smoother skin after just a few patches.